| Date | Location | Result | |
| 03/21/22 | Ocean Center - Daytona Beach, Fla. | Middle Tennessee 76, Boston U. 46 | Box score |
| 03/20/22 | Ocean Center - Daytona Beach, Fla. | Boston U. 71, UNC Greensboro 68 | Box score |
| 03/06/22 | Annapolis, MD | Navy 85, Boston U. 80 (OT) | Box score |
| 03/03/22 | Boston, MA | Boston U. 76, Loyola Maryland 64 | Box score |
| 02/26/22 | Lewisburg, PA | Bucknell 89, Boston U. 78 | Box score |
| 02/23/22 | Boston, MA | Boston U. 76, Lafayette 60 | Box score |
| 02/19/22 | Hamilton, NY | Colgate 72, Boston U. 53 | Box score |
| 02/16/22 | Worcester, MA | Boston U. 78, Holy Cross 65 | Box score |
| 02/12/22 | Boston, MA | Boston U. 85, American 67 | Box score |
| 02/09/22 | Boston, MA | Boston U. 75, Army West Point 74 | Box score |
| 02/05/22 | Bethlehem, PA | Boston U. 80, Lehigh 74 | Box score |
| 01/31/22 | Boston, MA | Holy Cross 75, Boston U. 70 | Box score |
| 01/28/22 | Boston, MA | Boston U. 76, Colgate 72 | Box score |
| 01/26/22 | Easton, PA | Boston U. 81, Lafayette 62 | Box score |
| 01/22/22 | Boston, MA | Boston U. 80, Lehigh 74 | Box score |
| 01/19/22 | Baltimore, MD | Boston U. 67, Loyola Maryland 50 | Box score |
| 01/16/22 | Boston, MA | Navy 72, Boston U. 65 | Box score |
| 01/13/22 | West Point, NY | Army West Point 73, Boston U. 63 | Box score |
| 01/10/22 | Washington, DC | Boston U. 79, American 53 | Box score |
| 01/07/22 | Boston, MA | Loyola Maryland 66, Boston U. 58 | Box score |
| 01/04/22 | Annapolis, MD | Navy 83, Boston U. 71 | Box score |
| 01/01/22 | Boston, MA | Boston U. 63, Bucknell 61 | Box score |
| 12/18/21 | Boston, MA | Marist 84, Boston U. 79 (OT) | Box score |
| 12/11/21 | Hanover, NH | Boston U. 65, Dartmouth 62 | Box score |
| 12/08/21 | Boston, MA | Boston U. 72, UMass Lowell 62 | Box score |
| 12/04/21 | Boston, MA | Boston U. 68, Binghamton 63 | Box score |
| 12/01/21 | Washington, DC | Boston U. 56, George Washington 54 | Box score |
| 11/28/21 | Boston, MA | Boston U. 61, Merrimack 60 | Box score |
| 11/24/21 | Tallahassee, FL | Florida St. 81, Boston U. 80 (OT) | Box score |
| 11/22/21 | Jacksonville, FL | Boston U. 72, Sam Houston 59 | Box score |
| 11/21/21 | Jacksonville, FL | Boston U. 76, Northern Ill. 58 | Box score |
| 11/18/21 | West Hartford, CT | Boston U. 75, Hartford 70 | Box score |
| 11/16/21 | Boston, MA | Northeastern 49, Boston U. 48 | Box score |
| 11/12/21 | Boston, MA | Boston U. 85, Gordon 61 | Box score |
| 11/09/21 | Kingston, RI | Rhode Island 71, Boston U. 62 | Box score |